Living with HIV/AIDS can have a profound impact on individuals’ mental health and well-being, leading to depression, anxiety, and social isolation. Addressing the psychosocial impact of HIV/AIDS requires comprehensive approaches that prioritize mental health support, stigma reduction, and community-based interventions. By integrating mental health services into HIV/AIDS care, providing peer support, and fostering supportive environments, we can improve the quality of life for individuals living with HIV/AIDS and promote resilience and well-being.